Side effects are not excluded. However, significant adverse effects have rarely been observed under intended use. If the dosage is too high, so-called excessive local reactions with a diameter of more than 5 cm are possible. In this case, you should stop the treatment and consult your attending medical specialist. Only after the symptoms have subsided, you may continue with a reduced dose (next lower concentration). The same applies to strong general reactions such as an increase in body temperature over 38°C. In this case, you would have to review the further therapy plan with your specialist in charge as well.